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Xin Yi
Ph.D., Assistant Professor
Department of Mechanics and Engineering Science,
College of Engineering, Peking University


2008-2014, Ph.D. in Mechanical Engineering, Brown University 

2005-2008, M.Sci. in Solid Mechanics, Peking University

2001-2005, B. Eng. in Mechanical Engineering, Peking University


Peking University, Assistant Professor, College of Engineering, 11/2016–present

Dartmouth College, Postdoctoral Associate, 07/2016–11/2016

Brown University, Postdoctoral Associate, 2014–2016

Research Interests

  • Micromechanics; Cell mechanics; Soft Matter; Cell interaction with nanomaterials


  For undergraduates

  ●  Mechanics of Materials (Spring' 18, Spring' 19, Spring' 20).

  For graduates

  ●  Introduction to Biophysics (Fall' 17), Applied Mathematics for Biomedicine (Fall' 18, Fall' 19).

Professional Activities

Reviewer for more than 30 scientific journals including ACS Nano, Acta Mechanica Sinica,  Advanced Functional Materials, Advanced Materials Interfaces, Advanced Science, Biophysical Journal, Extreme Mechanics Letters, International Journal of Solids and Structures, Journal of the Mechanics and Physics of Solids, Langmuir, Mechanics of Materials, Nanoscale, Physical Review Letters, Small, Soft Matter, and etc.


We are seeking highly motivated and creative postdoctoral researchers and graduate students interested in biophysics, soft matter system, and micro/nanoengineering. Interested candidates please visit our group webpage (Chinese version) for general information.

We also welcome undergraduate students to gain research experience in our group.

Selected Journal Publications


Google Scholar:

[1] Z. Wu and X. Yi, Structures and mechanical behaviors of soft nanotubes confining adhesive single or multiple elastic nanoparticles. Journal of the Mechanics and Physics of Solids 137, 103867 (2020).

[2] X. Tang, X. Shi, Y. Gan and X. Yi, Nanomechanical characterization of pressurized elastic fluid nanovesicles using indentation analysis. Extreme Mechanics Letters 34, 100613 (2020).

[3] L. Chen, W. Liu, L. Yu, Y. Cheng, K. Ren, H. Sui, X. Yi and H. Duan, Probabilistic and constitutive models for ductile-to-brittle transition in steels: A competition between cleavage and ductile fracture. Journal of the Mechanics and Physics of Solids 135, 103809 (2020).

[4] X. Tang, J. Wang and X. Yi, Force barrier for lipid sorting in the formation of membrane nanotubes. Journal of Applied Mechanics 86, 121002 (2019).

[5] Z. Dai, M. Yu, X. Yi, Z. Wu, F. Tian, Y. Miao, W. Song, S. He, E. Ahmad, S. Guo, C. Zhu, X. Zhang, Y. Li, X. Shi, R. Wang and Y. Gan, Chain-length- and saturation-tuned mechanics of fluid nanovesicles direct tumor delivery. ACS Nano 13, 7676 (2019).

[6] Y. Hui, X. Yi, F. Hou, D. Wibowo, F. Zhang, D. Zhao, H. Gao and C.-X. Zhao, Role of nanoparticle mechanical properties in cancer drug delivery. ACS Nano 13, 7410 (2019).

[7] W. Liu, L. Chen, Y. Cheng, L. Yu, X. Yi, H. Gao and H. Duan, Model of nanoindentation size effect incorporating the role of elastic deformation. Journal of the Mechanics and Physics of Solids 126, 245 (2019). 

[8] Z. Wu, H. Yuan, X. Zhang and X. Yi, Sidewall contact regulating the nanorod packing inside vesicles with relative volumes. Soft Matter 15, 2552 (2019).

[9] S. Li, Z. Yan, Z. Luo, Y. Xu, F. Huang, X. Zhang, X. Yi and T. Yue, Mechanics of the formation, interaction and evolution of membrane tubular structures. Biophysical Journal 116, 884 (2019).

[10] X. Li, J. Zhang, X. Yi, Z. Huang, P. Lv and H. Duan, Multimaterial microfluidic 3D printing of textured composites with liquid inclusions. Advanced Science 6, 1800730 (2019).

[11] X. Yi, G. Zou and H. Gao, Mechanics of cellular packing of nanorods with finite and non-uniform diameters. Nanoscale 10, 14090 (2018).

[12] X. Yi and H. Gao, Kinetics of receptor-mediated endocytosis of elastic nanoparticles. Nanoscale 9, 454 (2017).

[13] X. Yi and H. Gao, Incorporation of soft particles into lipid vesicles: Effects of particle size and elasticity. Langmuir 32, 13252 (2016).

[14] W. Zhu, A. von dem Bussche, X. Yi, Y. Qiu, Z. Wang, P. Weston, R. H. Hurt, A. B. Kane and H. Gao, Nanomechanical mechanism for lipid bilayer damage induced by carbon nanotubes confined in intracellular vesicles. Proceedings of the National Academy of Sciences of the U. S. A. 113, 12374 (2016).

[15] X. Yi and H. Gao, Cell interaction with graphene microsheets: Near-orthogonal cutting versus parallel attachment. Nanoscale 7, 5457 (2015).

[16] X. Yi, X. Shi and H. Gao, A universal law for cell uptake of one-dimensional nanomaterials. Nano Letters 14, 1049 (2014).

[17] X. Yi, X. Shi and H. Gao, Cellular uptake of elastic nanoparticles. Physical Review Letters 107, 098101 (2011).

[18] X. Yi and H. Duan, Surface stress induced by interactions of adsorbates and its effect on deformation and frequency of microcantilever sensors. Journal of the Mechanics and Physics of Solids 57, 1254 (2009).

[19] H. L. Duan, X. Yi, Z. Huang and J. Wang, A unified scheme for prediction of effective moduli of multiphase composites with interface effects. Part I: Theoretical framework. Mechanics of Materials 39, 81 (2007).

[20] H. Duan, X. Yi, Z. Huang and J. Wang, A unified scheme for prediction of effective moduli of multiphase composites with interface effects: Part II—Application and scaling laws. Mechanics of Materials 39, 94 (2007).