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Jeff Jianzhong Xi
Department of Biomedical Engineering
College of Engineering, Peking University,Beijing, 100871, China

Education Background

2004  Ph.D. Biomedical Engineering, University of California, Los Angeles

2000  M.S. Molecular and Cellular Biology, Tsinghua University

1996  B.S. Chemical Engineering, Beijing Institute of Technology

Professional Experience

1.Functional cell chips:

To develop a variety of high-throughput integrated chips, such as muscle-powered chip, cell migration chip, and others by use of the micro/nano technology


To perform quantitative detection of miRNA, and to study physiological function as well as regulatory mechanism of miRNA;


To create high-throughput RNAi screening platform, and to develop siRNA-based therapeutic approach.

Research Areas and Interests

Biochip and Cell Array Technology

siRNA, miRNA and other Noncoding RNA

Honors and Awards

1.Heritage Prize for Excellence in Creativity in Biomedical Engineering, Li’s Foundation, 2006,

2.National Outstanding Overseas Graduate Students?Chinese Education Ministry, 2005

3.Outstanding Doctoral Graduate Student, UCLA, 2004

4.Best Young Student/Investigator, MRS Spring Meeting, 2004

5.News articles regarding my achievement in Science, Nature, CNN, BBC, LA times, etc.

Selected Recent Publications

1.Li, Juan et al. Xi,J.*, Real-Time Polymerase Chain Reaction MicroRNA Detection Based on Enzymatic  Stem-Loop Probes Ligation. 2009, Anal. Chem,  2009, 81, 5446–5451.

2.Wang, J. et al.  Xi,J.*, Huang, Y.* A Chip-to-chip Nanoliter Microfluidic Dispenser. Lab-On-a-Chip, 2009, 9, 1831-1835.

3.Yao,Bo, et al. Xi, J.* Quantitative Analysis of Zeptomole MicroRNAs Based on Isothermal Ramification Amplification. RNA, 2009, 15, 1787-1794.

4. Xi, J*. Jacob, J. Montemagno, C*. Self-assembled Microdevices Driven by Muscle, Nature Materials, 2005, 4, 180-184.

5. Xi, J*. Ho, D. Chiu, B, Montemagno, C*. Lessons Learned from Engineering Biologically-active hybrid Nano/micro-devices. Advanced Functional Materials, 2005, 15,1233-1240

Selected Patented Clams

1.Jianzhong Xi, Bo Yao, Juan Li. A Method to Detect MicroRNAs. China, Patent of Invention (Pending).

2. Yanyi Huang, Jianzhong Xi, Jianbin Wang, Ying Zhou. The Microfluidic Dispenser and Its Preparation and Usage. China, Patent of Invention (Pending).